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X-WR-CALNAME:Djavad Mowafaghian Centre for Brain Health | DMCBH
X-ORIGINAL-URL:https://www.centreforbrainhealth.ca
X-WR-CALDESC:Events for Djavad Mowafaghian Centre for Brain Health | DMCBH
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DTSTART:20230312T100000
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DTSTART;TZID=America/Vancouver:20231006T110000
DTEND;TZID=America/Vancouver:20231006T120000
DTSTAMP:20231124T111057
CREATED:20230921T193033Z
LAST-MODIFIED:20230921T193101Z
UID:11887-1696590000-1696593600@www.centreforbrainhealth.ca
SUMMARY:Dr. Julia Schulze-Hentrich: At the nexus of genes\, aging and environment: Understanding transcriptomic and epigenomic regulation in health and disease
DESCRIPTION:Zoom option if unable to attend in person:\nZoom link here (click on “Join a meeting”)\nMeeting ID: 91512 289258\nPasscode: 289258\n\nThe DNA of every cell in our body contains the genes inherited from our parents and plays a crucial role in health and disease. While changes in the DNA itself are linked to monogenic diseases\, they often fail to explain complex disorders such as neurodegenerative diseases. This can potentially be explained by additional layers of gene regulation known to be stored “above” the DNA\, at the epigenetic level. Over the last years\, this relatively young research field has shown that molecular structures packaging DNA in the cell nucleus influence gene activity. The DNA itself as well as its packaging structure\, the so-called chromatin\, can be chemically modified in many ways and is highly dynamic. With these findings\, chromatin appears to be a central interface between genes and the environment\, and the development and progression of diseases could be decisively influenced by epigenetic changes. Our research group investigates which epigenetic modifications are associated with complex neurological diseases – in particular Parkinson’s and Huntington’s – and how environmental factors and aging have modulating effects on them. Here\, I will give an overview of current projects and highlight key findings of our work. \n 
URL:https://www.centreforbrainhealth.ca/events/dr-julia-schulze-hentrich/
LOCATION:Rudy North Lecture Theatre\, Djavad Mowafaghian Centre for Brain Health\, 2215 Wesbrook Mall\, Vancouver\, British Columbia\, V6T 1Z3\, Canada
CATEGORIES:Neuroscience Research Colloquium
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DTSTART;TZID=America/Vancouver:20231013T110000
DTEND;TZID=America/Vancouver:20231013T120000
DTSTAMP:20231124T111057
CREATED:20220426T222843Z
LAST-MODIFIED:20230822T172608Z
UID:8924-1697194800-1697198400@www.centreforbrainhealth.ca
SUMMARY:Dr. Denise Cai: The brain in motion: stability and flexibility of memory engrams across time and experience
DESCRIPTION:Zoom option if unable to attend in person:\nZoom link here (click on “Join a meeting”)\nMeeting ID: 91512 289258\nPasscode: 289258\n\nCreating stable memories is critical for survival. An animal relies on past learning to navigate its environment\, avoid dangerous situations\, and find needed resources. Because the environment is dynamic\, stable memories must be updated with new information to enable responses to changing threats (a specific danger) and rewards (such as food and water). The brain circuits involved in memory and learning require both stability and flexibility. Using in vivo calcium imaging and chemogenetics\, we demonstrate how new information is updated with past memories through co-reactivation of memory ensembles during offline periods including sleep.
URL:https://www.centreforbrainhealth.ca/events/dr-denise-cai/
LOCATION:Rudy North Lecture Theatre\, Djavad Mowafaghian Centre for Brain Health\, 2215 Wesbrook Mall\, Vancouver\, British Columbia\, V6T 1Z3\, Canada
CATEGORIES:Neuroscience Research Colloquium
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BEGIN:VEVENT
DTSTART;TZID=America/Vancouver:20231020T110000
DTEND;TZID=America/Vancouver:20231020T120000
DTSTAMP:20231124T111057
CREATED:20220604T014558Z
LAST-MODIFIED:20230822T172646Z
UID:9072-1697799600-1697803200@www.centreforbrainhealth.ca
SUMMARY:Dr. Randy McIntosh: Hidden Repertoires in Cognitive Function and Dysfunction
DESCRIPTION:Zoom option if unable to attend in person:\nZoom link here (click on “Join a meeting”)\nMeeting ID: 91512 289258\nPasscode: 289258\n\nA hidden repertoire is a functional configuration in the brain that supports behaviour but is seldom used. As a complex system\, the brain can show a broad range of configurations for the same function. This “many-to-one” property imparts our brain with resilience during normal operations but also in the face of adverse events\, such as damage or disease. I will cover the evidence for these repertoires and cover strategies for investigation\, and the implication for the I will also relate the existence of such repertoires to variations in the qualia of our experience.
URL:https://www.centreforbrainhealth.ca/events/dr-randy-mcintosh/
LOCATION:Rudy North Lecture Theatre\, Djavad Mowafaghian Centre for Brain Health\, 2215 Wesbrook Mall\, Vancouver\, British Columbia\, V6T 1Z3\, Canada
CATEGORIES:Neuroscience Research Colloquium
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