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X-WR-CALNAME:Djavad Mowafaghian Centre for Brain Health | DMCBH
X-ORIGINAL-URL:https://www.centreforbrainhealth.ca
X-WR-CALDESC:Events for Djavad Mowafaghian Centre for Brain Health | DMCBH
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DTSTART;TZID=America/Vancouver:20231201T110000
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SUMMARY:Dr. Mark Bevan: Dysregulation and rescue of subthalamic nucleus locomotor function in Huntington’s disease mice
DESCRIPTION:Zoom option if unable to attend in person:\nZoom link here (click on “Join a meeting”)\nMeeting ID: 91512 289258\nPasscode: 289258\n\nIn this seminar I will focus on our recent studies on the role of the subthalamic nucleus in motor control and its dysregulation in movement disorders.  We found that 1) subthalamic locomotor encoding and gait are highly dysregulated in Q175 Huntington’s disease (HD) mice 2) analogous gait deficits could be generated in wild type mice through optogenetic manipulation of subthalamic activity 3) subthalamic locomotor encoding and gait could be rescued in HD mice through suppression of subthalamic mutant huntingtin expression. Together\, these findings argue that subthalamic activity normally optimizes movement\, whereas dysregulated subthalamic activity contributes to gait deficits in HD and is a potential target for therapeutic intervention.
URL:https://www.centreforbrainhealth.ca/events/dr-mark-bevan/
LOCATION:Rudy North Lecture Theatre\, Djavad Mowafaghian Centre for Brain Health\, 2215 Wesbrook Mall\, Vancouver\, British Columbia\, V6T 1Z3\, Canada
CATEGORIES:Neuroscience Research Colloquium
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DTSTART;TZID=America/Vancouver:20231201T150000
DTEND;TZID=America/Vancouver:20231201T160000
DTSTAMP:20231124T105625
CREATED:20231101T161101Z
LAST-MODIFIED:20231110T010233Z
UID:12171-1701442800-1701446400@www.centreforbrainhealth.ca
SUMMARY:Quincy Collins: Exploring embryonic microglial responsiveness to maternal stress during pregnancy
DESCRIPTION:Join us for the UBC Behavioural Neuroscience Seminars (BNS)\, a lecture series featuring DMCBH trainees and professors in a casual setting. Talks take place from 3-4 pm every Friday in DMCBH 3402A-C and on Zoom. RSVP is not required. \nThis week’s speaker is Quincy Collins from the Rosin lab. \nZoom link: https://ubc.zoom.us/j/61318867702?pwd=VER4SC9FSGFzSW5TZHFKWi8vaUlEUT09 \nMeeting ID: 613 1886 7702\nPasscode: 1234 \n  \nIf you would like to be added to the mailing list to receive reminders each week\, please email Melody Salehzadeh (msalehzadeh@zoology.ubc.ca) and/or Jackson Schumacher (schumacher@psych.ubc.ca).
URL:https://www.centreforbrainhealth.ca/events/bns-quincy-collins/
LOCATION:DMCBH Room 3402\, 2215 Wesbrook Mall\, Vancouver\, British Columbia\, V6T 1Z3\, Canada
CATEGORIES:Behavioural Neuroscience Seminars
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