BEGIN:VCALENDAR VERSION:2.0 PRODID:-//Djavad Mowafaghian Centre for Brain Health | DMCBH - ECPv6.2.6//NONSGML v1.0//EN CALSCALE:GREGORIAN METHOD:PUBLISH X-WR-CALNAME:Djavad Mowafaghian Centre for Brain Health | DMCBH X-ORIGINAL-URL:https://www.centreforbrainhealth.ca X-WR-CALDESC:Events for Djavad Mowafaghian Centre for Brain Health | DMCBH REFRESH-INTERVAL;VALUE=DURATION:PT1H X-Robots-Tag:noindex X-PUBLISHED-TTL:PT1H BEGIN:VTIMEZONE TZID:America/Vancouver BEGIN:DAYLIGHT TZOFFSETFROM:-0800 TZOFFSETTO:-0700 TZNAME:PDT DTSTART:20210314T100000 END:DAYLIGHT BEGIN:STANDARD TZOFFSETFROM:-0700 TZOFFSETTO:-0800 TZNAME:PST DTSTART:20211107T090000 END:STANDARD BEGIN:DAYLIGHT TZOFFSETFROM:-0800 TZOFFSETTO:-0700 TZNAME:PDT DTSTART:20220313T100000 END:DAYLIGHT BEGIN:STANDARD TZOFFSETFROM:-0700 TZOFFSETTO:-0800 TZNAME:PST DTSTART:20221106T090000 END:STANDARD END:VTIMEZONE BEGIN:VEVENT DTSTART;TZID=America/Vancouver:20220318T110000 DTEND;TZID=America/Vancouver:20220318T120000 DTSTAMP:20231124T150529 CREATED:20210722T000000Z LAST-MODIFIED:20220304T235750Z UID:3740-1647601200-1647604800@www.centreforbrainhealth.ca SUMMARY:Dr. Kate Wassum: Amygdala circuitry in reward learning and decision making DESCRIPTION:To make adaptive decisions we must cast ourselves into the future and consider the outcomes of our potential choices. This prospective consideration is informed by our memories. I will discuss our lab’s recent work investigating the neural circuits responsible for encoding\, updating\, and retrieving reward memories for use in the considerations underlying decision making. We have taken a multifaceted approach to these investigations\, combining recording\, modern circuit dissection\, and behavioral tools. Our results are generally indicating that the basolateral amygdala\, midbrain\, and orbitofrontal cortex work in a circuit to participate in these functions. The cognitive symptoms underlying many psychiatric disorders result from a failure to appropriately learn about and/or anticipate potential future events\, making these basic science data relevant to the understanding and potential treatment of mental illness. \nZoom option if unable to attend in person: \n\nZoom link here (click on “Join a meeting”)\nMeeting ID: 99412 188589\nPasscode: 188589 URL:https://www.centreforbrainhealth.ca/events/dr-kate-wassum/ LOCATION:Rudy North Lecture Theatre\, Djavad Mowafaghian Centre for Brain Health\, 2215 Wesbrook Mall\, Vancouver\, British Columbia\, V6T 1Z3\, Canada CATEGORIES:Neuroscience Research Colloquium END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/Vancouver:20220311T110000 DTEND;TZID=America/Vancouver:20220311T120000 DTSTAMP:20231124T150529 CREATED:20210722T000000Z LAST-MODIFIED:20220301T230646Z UID:3739-1646996400-1647000000@www.centreforbrainhealth.ca SUMMARY:Dr. Rutsuko Ito: Ventral hippocampal circuits and the arbitration of approach-avoidance conflict DESCRIPTION:Approach-avoidance (AA) conflict resolution is a form of decision making that is fundamentally important for survival and requires the effective evaluation of affective stimuli or events with mixed outcomes (positive and negative). Despite the prevailing view of hippocampal involvement in learning and memory processes\, the hippocampus is also thought to be involved in the resolution of AA conflict by exaggerating the value of negative outcomes and increasing the tendency to avoid. Furthermore\, work from my laboratory has implicated the ventral\, but not the dorsal hippocampus\, in mediating affective processes involving learned AA conflict. In this talk\, I will be presenting a set of studies providing evidence of ventral hippocampal (vHPC) mediation of AA decision making when animals are exposed to affectively bivalent (conflicting) cues. I will also present chemogenetic evidence that the control over conflict-elicited AA  behaviours is subfield\, and pathway-specific\, with the investigation extending to the wider extrinsic connectivity of the vHPC with the lateral septum and ventral striatum. \nRudy North Lecture Theatre “Live” Screening\nZoom option if unable to attend in person: \n\nZoom link here (click on “Join a meeting”)\nMeeting ID: 99412 188589\nPasscode: 188589 URL:https://www.centreforbrainhealth.ca/events/dr-rutsuko-ito/ LOCATION:Rudy North Lecture Theatre\, Djavad Mowafaghian Centre for Brain Health\, 2215 Wesbrook Mall\, Vancouver\, British Columbia\, V6T 1Z3\, Canada CATEGORIES:Neuroscience Research Colloquium END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/Vancouver:20220218T110000 DTEND;TZID=America/Vancouver:20220218T120000 DTSTAMP:20231124T150529 CREATED:20210722T000000Z LAST-MODIFIED:20220301T222335Z UID:3737-1645182000-1645185600@www.centreforbrainhealth.ca SUMMARY:Dr. Jorn Diedrichsen: Exploring the role of the human cerebellum across functional domains DESCRIPTION:The cerebellum has evolved to support basic sensory-motor functions. In the human brain\, the cerebellar circuitry has dramatically expanded and contributes to virtually every cognitive function\, including working memory\, language\, and social cognition. Given its uniform cytoarchitecture\, it has long been hypothesized that the cerebellar circuit performs a common computation across all these functional domains. But what is this elusive transform? To ultimately answer this question we require a better understanding of the functional diversity of the cerebellum\, it’s connectivity to the neocortex\, and the relationship between cortical and cerebellar processes in each functional domain. I will present results from a number functional neuroimaging studies to characterize cerebellar function across cognitive domains to start to address these questions in a systematic fashion. \nRudy North Lecture Theatre “Live” Screening\nZoom option if unable to attend in person: \n\nZoom link here (click on “Join a meeting”)\nMeeting ID: 99412 188589\nPasscode: 188589 URL:https://www.centreforbrainhealth.ca/events/dr-jorn-diedrichsen/ LOCATION:British Columbia CATEGORIES:Neuroscience Research Colloquium END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/Vancouver:20220211T110000 DTEND;TZID=America/Vancouver:20220211T120000 DTSTAMP:20231124T150529 CREATED:20211016T053047Z LAST-MODIFIED:20220211T005633Z UID:7205-1644577200-1644580800@www.centreforbrainhealth.ca SUMMARY:Dr. Cheryl Wellington: Fluid biomarkers in neurology: Clinical and translational studies DESCRIPTION:Diseases of the brain are among the most challenging disorders to diagnose and treat. Unlike cancer\, where human tissue biopsy specimens are routinely collected\, brain disorders lack routine access to specimens that are essential to make progress in understanding pathophysiology and developing effective treatments. Currently\, most brain diseases are studied in living patients using neuroimaging or invasive cerebrospinal fluid (CSF) collection. New technologies now allow brain-derived substances to be measured in blood\, which is revolutionizing the field of neurology. The Wellington lab is currently collaborating with several local neurologists to develop and validate blood biomarkers for several acute and chronic neurological conditions. Highlights of our studies in Alzheimer’s Disease\, spinal cord injury and hypoxic ischemic brain injury will be presented. We are also present our program to develop and validate parallel assays that work in rodents to better understand the translational relevance of studies in animal models. \n\nZoom option if unable to attend in person\nZoom link here (click on “Join a meeting”)\nMeeting ID: 99412 188589\nPasscode: 188589 URL:https://www.centreforbrainhealth.ca/events/dr-cheryl-wellington/ LOCATION:Rudy North Lecture Theatre\, Djavad Mowafaghian Centre for Brain Health\, 2215 Wesbrook Mall\, Vancouver\, British Columbia\, V6T 1Z3\, Canada CATEGORIES:Neuroscience Research Colloquium END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/Vancouver:20220204T110000 DTEND;TZID=America/Vancouver:20220204T120000 DTSTAMP:20231124T150529 CREATED:20210722T000000Z LAST-MODIFIED:20220211T005611Z UID:3738-1643972400-1643976000@www.centreforbrainhealth.ca SUMMARY:Dr. John Kramer: Translational Research in Acute Spinal Cord Injury DESCRIPTION:This event will be held virtually: \nZoom link URL:https://www.centreforbrainhealth.ca/events/dr-john-kramer/ LOCATION:Online CATEGORIES:Neuroscience Research Colloquium END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/Vancouver:20211217T110000 DTEND;TZID=America/Vancouver:20211217T120000 DTSTAMP:20231124T150529 CREATED:20211016T052429Z LAST-MODIFIED:20211221T202501Z UID:7201-1639738800-1639742400@www.centreforbrainhealth.ca SUMMARY:Spontaneous activity\, memory replay\, and the default mode network DESCRIPTION:Spontaneous activity accounts for most of what the brain does and is likely to be key for information processing in the brain\, but its function is still quite mysterious. Two key spontaneous activity processes are the Default Mode Network (DMN)\, a set of areas that are most markedly connected and active during behavioural idleness\, and memory replay\, the spontaneous reactivation of neural patterns occurring during experience. In the Mohajerani lab\, we test the hypothesis that the DMN plays a key role in memory replay processes. This theory\, if confirmed\, would bring important conceptual advances: to memory studies\, as it would provide a mechanism supporting the formation and consolidation of complex memory representations. I will explore this theory by our ongoing studies of neural activity over the whole mouse cortex in animals running memory tasks. \nZoom option if unable to attend in person: \n\nZoom link here (Click on “Join a meeting”)\nMeeting ID: 95496 072083\nPasscode: 072083 URL:https://www.centreforbrainhealth.ca/events/dr-majid-mohajerani/ LOCATION:Rudy North Lecture Theatre\, Djavad Mowafaghian Centre for Brain Health\, 2215 Wesbrook Mall\, Vancouver\, British Columbia\, V6T 1Z3\, Canada CATEGORIES:Neuroscience Research Colloquium END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/Vancouver:20211210T110000 DTEND;TZID=America/Vancouver:20211210T120000 DTSTAMP:20231124T150529 CREATED:20211019T222822Z LAST-MODIFIED:20211221T202222Z UID:7212-1639134000-1639137600@www.centreforbrainhealth.ca SUMMARY:Unraveling microglial heterogeneity and stress responses in the embryonic hypothalamus DESCRIPTION:Zoom option if unable to attend in person: \n\nZoom link here (Click on “Join a meeting”)\nMeeting ID: 95496 072083\nPasscode: 072083 URL:https://www.centreforbrainhealth.ca/events/dr-jessica-rosin/ LOCATION:Rudy North Lecture Theatre\, Djavad Mowafaghian Centre for Brain Health\, 2215 Wesbrook Mall\, Vancouver\, British Columbia\, V6T 1Z3\, Canada CATEGORIES:Neuroscience Research Colloquium END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/Vancouver:20211203T110000 DTEND;TZID=America/Vancouver:20211203T120000 DTSTAMP:20231124T150529 CREATED:20211016T052702Z LAST-MODIFIED:20211221T202047Z UID:7202-1638529200-1638532800@www.centreforbrainhealth.ca SUMMARY:The effects of maternal immune activation on early development in an outbred strain of mice DESCRIPTION:Our lab is interested in the neural bases for social function\, and we use mouse models for diseases that have social deficits at their core. This talk will present our recent work looking at postnatal development\, juvenile behaviours and autophagy in a mouse model of perinatal infection. \nRudy North Lecture Theatre “Live” Screening\nZoom option if unable to attend in person: \n\nZoom link here (Click on “Join a meeting”)\nMeeting ID: 95496 072083\nPasscode: 072083 URL:https://www.centreforbrainhealth.ca/events/dr-tamara-franklin/ LOCATION:Rudy North Lecture Theatre\, Djavad Mowafaghian Centre for Brain Health\, 2215 Wesbrook Mall\, Vancouver\, British Columbia\, V6T 1Z3\, Canada CATEGORIES:Neuroscience Research Colloquium END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/Vancouver:20211119T110000 DTEND;TZID=America/Vancouver:20211119T120000 DTSTAMP:20231124T150529 CREATED:20210722T000000Z LAST-MODIFIED:20211117T002332Z UID:3734-1637319600-1637323200@www.centreforbrainhealth.ca SUMMARY:Reporting Options for Sexualized Violence DESCRIPTION:SVPRO is back for a second session! This session will focus on the different options that are available for reporting when sexualized violence has occurred. Not everyone wants to report after being impacted by sexualized violence\, and that’s completely okay. When folks do want to report\, it’s important that they know the full range of options and considerations. Join us to learn about UBC systems\, police reporting\, and human rights reporting systems\, when each may apply\, and how SVPRO supports people navigating these processes. \nZoom option if unable to attend in person: \n\nZoom link here (Click on “Join a meeting”)\nMeeting ID: 95496 072083\nPasscode: 072083 URL:https://www.centreforbrainhealth.ca/events/reporting-options-for-sexualized-violence/ LOCATION:Rudy North Lecture Theatre\, Djavad Mowafaghian Centre for Brain Health\, 2215 Wesbrook Mall\, Vancouver\, British Columbia\, V6T 1Z3\, Canada CATEGORIES:Neuroscience Research Colloquium END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/Vancouver:20211105T110000 DTEND;TZID=America/Vancouver:20211105T120000 DTSTAMP:20231124T150529 CREATED:20210722T000000Z LAST-MODIFIED:20220301T222553Z UID:3733-1636110000-1636113600@www.centreforbrainhealth.ca SUMMARY:Development of a whole-brain memory trace pipeline for activity-dependent tagging murine lines DESCRIPTION:We previously created a mouse model to permanently label neurons activated during learning\, the ArcCreERT2 mice (Denny et al.\, 2014\, Neuron). In our first publication\, we extensively characterized the ArcCreERT2 mice and manipulated various parameters to correlate behavioral expression with memory tagging. Using contextual fear conditioning (CFC)\, we showed that mice re-exposed to a fearful context freeze more and have a greater percentage of reactivated cells in the dentate gyrus (DG) and in CA3 than mice exposed to a novel context. Overall\, we found that context\, time\, adult hippocampal neurogenesis\, and stress impact cognition and mood\, and these alterations are paralleled by changes in memory trace activation in the hippocampus. In our more recent studies\, we have investigated how disease states and pharmacological manipulations impact memory traces (Perusini et al.\, 2017; Mastrodonato et al.\, 2018; Lacagnina et al.\, 2019; Leal Santos et al.\, 2021). \nOur ongoing/planned projects are to identify: 1) how individual memories are stored throughout the entire brain using a novel whole-brain imaging pipeline we have recently developed\, 2) how multiple memories are co-stored throughout the brain using a new activity-dependent viral strategy\, and 3) how disease states impact memories\, often resulting in memory loss. \nRudy North Lecture Theatre “Live” Screening\nZoom option if unable to attend in person: \n\nZoom link  here (Click on “Join a meeting”)\nMeeting ID: 95496 072083\nPasscode: 072083 URL:https://www.centreforbrainhealth.ca/events/dr-christine-denny/ LOCATION:Rudy North Lecture Theatre\, Djavad Mowafaghian Centre for Brain Health\, 2215 Wesbrook Mall\, Vancouver\, British Columbia\, V6T 1Z3\, Canada CATEGORIES:Neuroscience Research Colloquium END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/Vancouver:20211029T110000 DTEND;TZID=America/Vancouver:20211029T120000 DTSTAMP:20231124T150529 CREATED:20210722T000000Z LAST-MODIFIED:20211106T045737Z UID:3732-1635505200-1635508800@www.centreforbrainhealth.ca SUMMARY:Genome-wide approaches to understanding microglia identity and function DESCRIPTION:Microglia are the macrophages of the brain and participate to its development\, homeostasis\, and defense against pathogens and injuries. Notably\, genetic evidence suggests that they are critically involved in neurodegenerative diseases\, including Alzheimer’s disease. However\, our knowledge of the molecular processes that regulate these cells in the brain remains very rudimentary. \nOver the past few years\, we have concentrated our efforts on trying to understand how gene regulation is achieved in microglia. In particular\, we provided evidence using mouse microglia that signaling factors in the brain provide important regulatory input that enable microglia to acquire their cellular identity. Importantly\, our recent work on human microglia shows that axes of signaling pathways – transcription factors that shape the microglial epigenome and transcriptional characteristics are relatively well conserved between the mouse and human. My talk will provide an overview of these recent findings\, and elaborate on the current approaches that we use to gain a better understanding of the epigenomic mechanisms underlying the different cellular functions of microglia in the brain. \nZoom option if unable to attend in person: \n\nZoom link here (Click on “Join a meeting”)\nMeeting ID: 95496-072083\nPasscode: 072083 URL:https://www.centreforbrainhealth.ca/events/dr-david-gosselin/ LOCATION:Rudy North Lecture Theatre\, Djavad Mowafaghian Centre for Brain Health\, 2215 Wesbrook Mall\, Vancouver\, British Columbia\, V6T 1Z3\, Canada CATEGORIES:Neuroscience Research Colloquium END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/Vancouver:20211022T110000 DTEND;TZID=America/Vancouver:20211022T120000 DTSTAMP:20231124T150529 CREATED:20210722T000000Z LAST-MODIFIED:20211106T045813Z UID:3731-1634900400-1634904000@www.centreforbrainhealth.ca SUMMARY:The olfactory mosaic: How diverse networks shape perception DESCRIPTION:Our perception of the world begins with stimuli in the environment but is then dramatically shaped by our expectations\, past experience\, and internal state.  Olfactory perception is especially sensitive to these kinds of modulation.  In fact\, input from a diverse network of brain regions conveying multisensory\, homeostatic and experience-dependent information converges on the olfactory system as early as the first stages of odor processing.  This talk will describe our work over the past few years on how activity in non-olfactory regions shapes odor coding and perception.  What you smell is not necessarily what you get. \nRudy North Lecture Theatre “Live” Screening \nZoom option if unable to attend in person: \n\nZoom link here (Click on “Join a meeting”)\nMeeting ID: 95496 072083\nPasscode: 072083 URL:https://www.centreforbrainhealth.ca/events/dr-donald-wilson/ LOCATION:Rudy North Lecture Theatre\, Djavad Mowafaghian Centre for Brain Health\, 2215 Wesbrook Mall\, Vancouver\, British Columbia\, V6T 1Z3\, Canada CATEGORIES:Neuroscience Research Colloquium END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/Vancouver:20211015T110000 DTEND;TZID=America/Vancouver:20211015T120000 DTSTAMP:20231124T150529 CREATED:20210901T003804Z LAST-MODIFIED:20211106T050007Z UID:6448-1634295600-1634299200@www.centreforbrainhealth.ca SUMMARY:Preventing and Responding to Sexualized Violence DESCRIPTION:  \n\nZoom option if unable to attend in person:\nZoom link here (click on “Join a meeting”)\nMeeting ID: 95496 072083\nPasscode: 072083\n\nSVPRO will present UBC’s approach to preventing and responding to sexualized violence\, with a focus on key principles for supporting survivors. The presentation will include what constitutes sexualized violence and prohibited relationships\, standards and considerations for safe and respectful working and learning environments\, and how to respond to a disclosure\, with approaches to help mitigate impacts and reduce harm. This presentation is part one of a two-part series; part 2 (November 19) will focus on reporting options. URL:https://www.centreforbrainhealth.ca/events/preventing-and-responding-to-sexualized-violence/ LOCATION:Rudy North Lecture Theatre\, Djavad Mowafaghian Centre for Brain Health\, 2215 Wesbrook Mall\, Vancouver\, British Columbia\, V6T 1Z3\, Canada CATEGORIES:Neuroscience Research Colloquium END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/Vancouver:20211008T110000 DTEND;TZID=America/Vancouver:20211008T120000 DTSTAMP:20231124T150529 CREATED:20211016T045905Z LAST-MODIFIED:20211106T050044Z UID:7198-1633690800-1633694400@www.centreforbrainhealth.ca SUMMARY:Brain-Tech 2021 Hackathon: student teams innovation showcase DESCRIPTION:This colloquium will present innovation from the top student teams of the Brain-Tech 2021: Idea Generation and Hackathon for Brain Wellness. The Hackathon was hosted by the Dynamic Brain Circuits in Health and Disease Cluster\, the BC Brain Wellness Program\, and the Djavad  Mowafaghian Centre for Brain Health. The Brain-Tech 2021 winners will discuss and demo their work which aims to improve brain wellness. URL:https://www.centreforbrainhealth.ca/events/brain-tech-2021-hackathon-student-teams-innovation-showcase/ LOCATION:Rudy North Lecture Theatre\, Djavad Mowafaghian Centre for Brain Health\, 2215 Wesbrook Mall\, Vancouver\, British Columbia\, V6T 1Z3\, Canada CATEGORIES:Neuroscience Research Colloquium END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/Vancouver:20211001T110000 DTEND;TZID=America/Vancouver:20211001T120000 DTSTAMP:20231124T150529 CREATED:20210831T205406Z LAST-MODIFIED:20211221T202400Z UID:6427-1633086000-1633089600@www.centreforbrainhealth.ca SUMMARY:Sex-specific impact of immune signaling on adolescent neural and social development DESCRIPTION:  \n\nJoin in person in the auditorium or via the zoom option. The presenter will be remote.\nZoom link here (click on “Join a meeting”)\nMeeting ID:  95496 072083\nPasscode: 072083\n\nIn this presentation\, Dr. Ashley Kopec will discuss published work examining the role of microglia\, the resident immune cells in the brain\, in neural and social development during adolescence in male and female rats. Then\, she will discuss unpublished work aimed at understanding how opioid exposures during adolescence interact with microglia-mediated development to alter future reward-related behaviors. \nThere will be a virtual trainee meeting with Dr. Kopec immediately following her talk (~noon). If you would like to attend the trainee meeting please email annie.ciernia@ubc.ca to sign up. There are limited spots available on a first come first serve basis. URL:https://www.centreforbrainhealth.ca/events/dr-ashley-kopec/ LOCATION:Rudy North Lecture Theatre\, Djavad Mowafaghian Centre for Brain Health\, 2215 Wesbrook Mall\, Vancouver\, British Columbia\, V6T 1Z3\, Canada CATEGORIES:Neuroscience Research Colloquium END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/Vancouver:20210917T110000 DTEND;TZID=America/Vancouver:20210917T120000 DTSTAMP:20231124T150529 CREATED:20210722T000000Z LAST-MODIFIED:20211106T050246Z UID:3730-1631876400-1631880000@www.centreforbrainhealth.ca SUMMARY:Canadian Open Neuroscience Platform Scholars Update DESCRIPTION:Host: Jeff LeDue\nSpeaker: GPN CONP Scholars URL:https://www.centreforbrainhealth.ca/events/canadian-open-neuroscience-platform-scholars-update/ LOCATION:Rudy North Lecture Theatre\, Djavad Mowafaghian Centre for Brain Health\, 2215 Wesbrook Mall\, Vancouver\, British Columbia\, V6T 1Z3\, Canada CATEGORIES:Neuroscience Research Colloquium END:VEVENT END:VCALENDAR